Dementia – PossibleThreat Articles

Brain fat, not just plaques, may be the hidden driver of Alzheimer’s

September 24, 2025 0 Comments #039, Alternative Medicine, amp, Dementia, Diseases and Conditions, Infant and Preschool Learning, Intelligence, Language Acquisition, Pharmacology, s Healthcare, Today&amp

For decades, scientists believed Alzheimer’s was driven mainly by sticky protein plaques and tangles in the brain. Now Purdue researchers have revealed a hidden culprit: fat. They found that brain immune cells can become clogged with fat, leaving them too weak to fight off disease. By clearing out this fat and restoring the cells’ defenses, researchers may have uncovered an entirely new way to combat Alzheimer’s — shifting the focus from plaques alone to how the brain handles fat.

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Hidden brain signal reveals Alzheimer’s years before symptoms

September 23, 2025 0 Comments #039, Alzheimer&amp, amp, Dementia, Diseases and Conditions, Immune System, Memory, s, s Health, Social Psychology, Women&amp, Workplace Health

A new study has revealed that TSPO, a protein linked to brain inflammation, rises long before Alzheimer’s symptoms appear. Researchers tracked the protein in genetically engineered mice and confirmed the results in human brain tissue from Colombian families with a known Alzheimer’s mutation. They found unusually high levels of TSPO in microglia clustered around plaques, particularly in women. This discovery not only deepens our understanding of the disease but also sparks the possibility of using TSPO to detect and treat Alzheimer’s far earlier than ever before.

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Want a younger brain? Harvard researchers say eat like this

September 23, 2025 0 Comments #039, Alzheimer&amp, amp, Consumer Behavior, Dementia, Diet and Weight Loss, Healthy Aging, Nutrition, Nutrition Research, s, s Research

Researchers have shown that a green-Mediterranean diet can help slow brain aging. By analyzing data from the DIRECT PLUS trial, scientists found reduced levels of proteins tied to faster brain decline among those consuming green tea and Mankai. The results point to anti-inflammatory compounds as key protectors of brain health. This diet may be a powerful tool for preserving cognitive function.

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High-salt diet promotes cognitive impairment through the Alzheimer-linked protein tau

October 24, 2019 0 Comments Alzheimer's Research, Blood Clots, Brain Tumor, Dementia, Disorders and Syndromes, Hypertension, Intelligence, neuroscience

Investigators sought to understand the series of events that occur between salt consumption and poor cognition and concluded that lowering salt intake and maintaining healthy blood vessels in the brain may 'stave off' dementia. Accumulation of tau deposits has been implicated in the development of Alzheimer's disease in humans.

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Greater understanding of Alzheimer's disease

October 23, 2019 0 Comments Alzheimer's, Alzheimer's Research, Crohn's Disease, Dementia, Diseases and Conditions, Disorders and Syndromes, Healthy Aging, Memory

Scientists have made an important discovery in understanding the role a particular protein plays to impair memory in Alzheimer's disease, which could lead to more effective treatment in future.

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In Alzheimer's research, scientists reveal brain rhythm role

October 23, 2019 0 Comments Alzheimer's, Alzheimer's Research, Brain Tumor, Brain-Computer Interfaces, Dementia, Nervous System, neuroscience, Psychology Research

In the years since her lab discovered that exposing Alzheimer's disease model mice to light flickering at the frequency of a key brain rhythm could stem the disorder's pathology, a neuroscientist and her team have been working to understand what the phenomenon may mean both for fighting the disease and understanding of how the brain works.

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Dementia patients' adult kids diagnosed earlier than their parents

October 22, 2019 0 Comments Alzheimer's, Alzheimer's Research, Child Psychology, Dementia, Diabetes, Disorders and Syndromes, Elder Care, Healthy Aging

A new study indicates that people with dementia — whose parents also had dementia — develop symptoms an average of six years earlier than their parents.

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Combination of more hospitalizations and brain pathologies linked to faster cognitive decline

October 22, 2019 0 Comments Alzheimer's, Alzheimer's Research, Behavior, Brain Tumor, Dementia, Elder Care, Healthy Aging, Intelligence

Older people who experienced more hospitalizations and also had more Alzheimer's pathology in their brain experienced the fastest rates of cognitive decline, according to a new study.

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A blood factor involved in weight loss and aging

October 22, 2019 0 Comments Brain Tumor, Dementia, Diet and Weight Loss, Dieting and Weight Control, Hypertension, Intelligence, Nutrition Research, Obesity

Aging can be delayed through lifestyle changes (physical exercise, restricting calorie intake, etc.). Researchers have elucidated the properties of a molecule in the blood – GDF11 – whose mechanisms were previously unknown. In a mouse model, they showed that this molecule could mimic the benefits of certain calorie restrictions – dietary regimens that have proven their efficacy in reducing cardiovascular disease, preventing cancer and increasing neurogenesis in the brain.

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Gene variants influence size of brainstem, other structures

October 21, 2019 0 Comments Alzheimer's, Alzheimer's Research, Dementia, Diseases and Conditions, Disorders and Syndromes, Healthy Aging, Intelligence, Parkinson's Research

Three-hundred researchers have identified 48 common genetic variants that are associated with the size of the brainstem and other subcortical structures deep within the brain. This is the first step toward understanding how to devise treatments for disorders affecting these structures.

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