Salmonella causing bloodstream infections in central Africa resistant to nearly all drugs

The first extensively drug-resistant (XDR) strains of Salmonella Typhimurium, a pathogen which is responsible for millions of bloodstream infections per year in sub-Saharan Africa, have been identified in the Democratic Republic of Congo (DRC). Drug-resistance has increased in successive groups of S. Typhimurium over time. These new strains are resistant to all but one of the commonly available drugs in the DRC, with one sample showing reduced susceptibility to this final antibiotic.

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Few people with peanut allergy tolerate peanut after stopping oral immunotherapy

Studies have shown that peanut oral immunotherapy (OIT) — ingesting small, controlled amounts of peanut protein — can desensitize adults and children and prevent allergic reactions, but the optimal duration and dose is unknown. In a study that followed participants after successful OIT, discontinuing OIT or continuing OIT at a reduced dose led to a decline in its protective effects. The study also found that blood tests administered before OIT could predict the success of therapy.

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