New drug-delivery technology promises efficient, targeted cancer treatment
A precise and non-toxic treatment that targets lung cancer cells at the nanoscale is able to effectively kill the cells even at a low dose.
Read moreLung Cancer
Aggressive form of breast cancer influenced by dual action of genes and RNA
Women with an aggressive, less-common type of breast cancer, known as triple-negative, versus a more common form of the disease, could be differentiated from each other by a panel of 17 small RNA molecules that are directly influenced by genetic alterations typically found in cancer cells.
Read moreMen with breast cancer face high mortality rates
Men with breast cancer are more likely to die than their female counterparts, across all stages of disease, with the disparity persisting even when clinical characteristics, such as cancer types, treatment and access to care are considered, according to a new study.
Read moreMarked slowdown of cell division rates in old age
In a novel study comparing healthy cells from people in their 20s with cells from people in their 80s, researchers say they have documented that cell division rates appear to consistently and markedly slow down in humans at older ages.
Read moreBreaking the stroma barrier: Study shows a new way to hit cancer with radiation
Chemotherapy and radiation therapy are commonly used to treat cancer, but are not always effective and can have toxic side effects. Researchers tested a new radiotherapy technique that sends alpha-emitting particles to stroma cells in pancreatic tumors. The method slowed tumor growth in mice with minimal side effects, pointing to a new potential treatment option in the future for patients with pancreatic cancer.
Read moreGAS7 protein allows cells to eat
Phagocytosis can be viewed as a primitive immune system used by all cells. When a pathogen is near the cell, the cell membrane will deform to engulf the pathogen and dispose of it. Researchers have found that a two-dimensional sheet formed by the protein GAS7 is critical for this process, identifying through crystallography and microscopy two key hydrophilic loops in the protein.
Read moreCreatine powers T cells' fight against cancer
The study, conducted in mice, is the first to show that creatine uptake is critical to the anti-tumor activities of killer T cells, the foot soldiers of the immune system.
Read moreNew diagnostic method finds aggressive tumors
Researchers have developed a new cheap method that can identify highly heterogeneous tumors that tend to be very aggressive, and therefore need to be treated more aggressively.
Read moreA higher resolution image of human lung development
Researchers provide clearer picture of how lungs develop and discover novel markers to differentiate populations of lung cells implicated in lung diseases of premature babies.
Read moreA compound effective to chemotherapy-resistant cancer cells identified
A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity.
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