PTSD nearly doubles infection risk

A new study is the first to examine the relationship between post-traumatic stress disorder (PTSD) and dozens of infection types in a nationwide cohort. Researchers found that PTSD affects infection risks for men and women differently, having, for example, more of an effect on a woman's risk of urinary tract infection and a man's risk of skin infection.

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Widely available drug reduces head injury deaths

A low cost and widely available drug could reduce deaths in traumatic brain injury patients by as much as 20%, depending on the severity of injury, according to a major study. The researchers say that tranexamic acid (TXA), a drug that prevents bleeding into the brain by inhibiting blood clot breakdown, has the potential to save hundreds of thousands of lives.

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Repeated febrile convulsions linked to epilepsy and psychiatric disorders

The risk of febrile convulsions increases with the child's fever, and children who suffer from repeated febrile convulsions during their first year of life have an increased risk of developing epilepsy and psychiatric disorders later in life. This is shown by a comprehensive register-based study. In the study, almost 76,000 Danish children who have been suffering from febrile convulsions have been followed for more than 30 years.

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Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia

A systematic review and meta-analysis suggests outdoor activities were more clinically effective than anti-psychotic medication for treating physical aggression in patients with dementia. For patients with physical agitation, massage and touch therapy were more efficacious than usual care or caregiver support.

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Microbleeds may worsen outcome after head injury

Using advanced imaging, researchers have uncovered new information regarding traumatic microbleeds, which appear as small, dark lesions on MRI scans after head injury but are typically too small to be detected on CT scans. The findings published in Brain suggest that traumatic microbleeds are a form of injury to brain blood vessels and may predict worse outcomes. The study was conducted in part by scientists at the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.

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Brain scans may provide clues to suicide risk

Researchers have identified brain circuitry differences that might be associated with suicidal behavior in individuals with mood disorders. The study provides a promising lead toward tools that can predict which individuals are at the highest risk for suicide.

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Serum neurofilament is a discriminative biomarker between frontotemporal dementia and psychiatric disorders

Early symptoms of frontotemporal dementia are often confused with symptoms occurring in psychiatric disorders. Researchers show that serum neurofilament levels can be used as a diagnostic tool to differentiate between these conditions.

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