Q-suite motor assessment tool promising for evaluating Huntington's disease

In clinical trials of adults with Huntington's disease (HD) the Q-Suite Motor Assessment Tool (Q-Motor) has proven to be helpful to detect and quantitate subtle motor abnormalities. With the anticipated arrival of preventive gene therapies that will most likely be administered to young children known to be carriers of the HD mutation, it is crucial to have a means to evaluate motor abilities in children that is sensitive to the child's stage of development.

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To learn English, bilingual children need robust vocabulary from parents and caregivers

A study examining parents' vocabulary and grammar as an influence on children's acquisition of English, finds that the quality of child-directed speech depends on the speaker's language proficiency. Children who hear a rich vocabulary acquire a rich vocabulary and children who hear a rich vocabulary in full sentences acquire the ability to put their words together in full sentences. Findings have broad implications for immigrant parents' language choices at home and for staffing practices in early care and education centers.

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New study challenges our understanding of premature aging

Disturbances in the function of mitochondrial DNA can accelerate the ageing process in ways that are different than previously thought, according to a new study. Offering a new perspective to ageing, the researchers suggest that accelerated ageing is the result of abnormal cell nucleotide levels and compromised nuclear DNA maintenance.

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How fungus-farming ants could help solve our antibiotic resistance problem

For the last 60 million years, fungus-growing ants have farmed fungi for food. In their cultivation of those fungi, they've successfully relied on bacteria-produced antimicrobial ingredients to protect their crops from other species of parasitic fungi. Now, researchers say they are looking to these ants to find new ways to stop or slow the evolution of antibiotic resistance that now presents a threat to modern medicine.

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Researchers perform thousands of mutations to understand amyotrophic lateral sclerosis

Researchers have used a technique called high-throughput mutagenesis to study Amyotrophic Lateral Sclerosis (ALS), with unexpected results. Results showed that aggregation of TDP-43 is not harmful but actually protects cells, changing our understanding of ALS and opening the door to radically new therapeutic approaches.

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