Popular sugar substitute linked to brain cell damage and stroke risk

Erythritol, a widely used sugar substitute found in many low-carb and sugar-free products, may not be as harmless as once believed. New research from the University of Colorado Boulder reveals that even small amounts of erythritol can harm brain blood vessel cells, promoting constriction, clotting, and inflammation—all of which may raise the risk of stroke.

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A blood factor involved in weight loss and aging

Aging can be delayed through lifestyle changes (physical exercise, restricting calorie intake, etc.). Researchers have elucidated the properties of a molecule in the blood – GDF11 – whose mechanisms were previously unknown. In a mouse model, they showed that this molecule could mimic the benefits of certain calorie restrictions – dietary regimens that have proven their efficacy in reducing cardiovascular disease, preventing cancer and increasing neurogenesis in the brain.

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Evidence of behavioral, biological similarities between compulsive overeating and addiction

Does yo-yo dieting drive compulsive eating? There may be a connection. According to researchers the chronic cyclic pattern of overeating followed by undereating, reduces the brain's ability to feel reward and may drive compulsive eating. This finding suggests that future research into treatment of compulsive eating behavior should focus on rebalancing the mesolimbic dopamine system — the part of the brain responsible for feeling reward or pleasure.

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