A new study has found that obtaining a second opinion from pathologists who are board certified or have fellowship training in dermatopathology can help improve the accuracy and reliability of diagnosing melanoma.
Read moreChronobiologists show how critical the sleep-wake cycle is for protein and phosphorylation dynamics in synapses to ultimately regulate its activity.
Read moreThe technique makes use of the fact that people inherit two copies or ''alleles'' of virtually every gene, one from the mother and one from the father. The new method compares activity levels of maternal and paternal alleles across the genome and detects when the activity of an allele lies far enough outside the normal range to be a plausible cause of disease.
Read moreNew research has found that a newly tested medical device, called Sleeveballoon, mimics the effects of traditional bariatric surgery in rodents and produces impressive results on body weight, fatty liver and diabetes control.
Read moreSome forms of sudden infant death syndrome stem from a genetic mutation that keeps infants from processing lipids in milk, a new study has discovered. The build-up of unprocessed fatty material disrupts heart functions. While no treatments are yet available, the finding could help in genetic screening. Drugs are also being tested to see if they can help.
Read moreThe largest study of its kind into childhood developmental disorders has discovered that jumping genes cause genetic changes in some patients with undiagnosed neurodevelopmental diseases. The research enabled genetic diagnoses for three children with previously undiagnosed rare developmental diseases, enrolled in the Deciphering Developmental Disorders project. Reported in Nature Communications, these diagnoses will help the families access support and understand the disease risks for any future children.
Read moreFor years, scientists thought that these powerful sedatives, which are used to treat anxiety, muscle spasms, and sleeping disorders, worked alone to calm nerves. Now, researchers show that this view of the drugs and the neural circuits they affect may have to change. In a study of mice, scientists discovered that both may need the assistance of a 'sticky' gene, named after a mythological figure, called Shisa7.
Read moreThe first comprehensive look at the immune system of the fetal gut shows that it is far more developed before birth, and could help develop new maternal vaccines and reveal if we are predisposed to autoimmune diseases before birth.
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