Mapping normal breast development to better understand cancer

Breast cancer is one of the most prevalent cancers, and some forms rank among the most difficult to treat. Its various types and involvement of many different cells makes targeting such tumors difficult. Now, researchers have used a state-of-the-art technology to profile each cell during normal breast development in order to understand what goes wrong in cancer.

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New mechanism in the liver helps prevent invasive fungal infections

An expert in intravital microscopy is making breakthroughs in invasive fungal infections. He has discovered a pathway by which liver macrophages capture fungi before dissemination to target organs like the brain. This not only provides an explanation as to why individuals with liver disease have enhanced risk of fungal infection, but also points to therapeutic options to prevent these infections, which kill 1.5 million people annually.

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Scientists discover new antibiotic in tropical forest

Scientists have discovered an antibiotic produced by a soil bacterium from a Mexican tropical forest that may help lead to a 'plant probiotic,' more robust plants and other antibiotics. Probiotics, which provide friendlier bacteria and health benefits for humans, can also be beneficial to plants, keeping them healthy and more robust. The new antibiotic, known as phazolicin, prevents harmful bacteria from getting into the root systems of bean plants.

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Common denominator that triggers asthma in favorable environments

Some so-called pro-allergic environments strongly promote the development of asthma and are responsible for the dramatic increase in the prevalence of asthma, especially in industrialized countries. Researchers at the GIGA of the University of Liège have identified how all these pro-allergic environments act in the same way on the pulmonary immune system to induce the development of allergic asthma.

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Initiating breastfeeding in vulnerable infants

The benefits of breastfeeding for both mother and child are well-recognized, including for late preterm infants (LPI). But because LPI do not have fully developed brains, they may experience difficulties latching and/or sustaining a latch on the breast to have milk transfer occur. This means that these infants are at high risk for formula supplementation and/or discontinuation of breastfeeding.

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