Researchers have identified a group of genetic variants related to the starting point of Parkinson's disease. These results, published in the journal Movement Disorders, will enable delimiting the research on new therapeutic targets, and could have implications in the diagnosis of the disease.
Read moreTreatments have been hard to pinpoint for a rare neurological disease called Charcot-Marie-Tooth, in part because so many variations of the condition exist. So far, mutations on more than 90 genes have been positively linked to the disorder; a patient needs just one of those mutations for the disease to emerge. Scientists just moved a step closer to finding a possible root cause.
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Contrary to previous advice, five new systematic reviews suggest that most people can continue to eat red and processed meat as they do now. The major studies have found cutting back has little impact on health.
Children under 5 years of age in Africa are much more likely to die as a direct result of poor health linked to air pollution, unsafe water, lack of sanitation, increased family size, and environmental degradation, according to the first continent-wide investigation of its kind. An international team of researchers have analysed data to break down the correlation between increased child mortality, environmental degradation,and population density of all countries across the African continent.
Read moreImmune therapy added to chemotherapy improves pathological complete response in patients with early triple negative breast cancer, according to new results from the KEYNOTE-522 trial. Interim results from the study, which is the first phase III trial of immunotherapy in early breast cancer, also indicated an improvement in event-free survival.
Read morePatients with severe asthma which is not controlled with standard treatment — leaving them at risk of severe asthma attacks — could benefit from using a single inhaler combining three, instead of 2 therapies, according to two phase 3 randomized controlled trials with over 2,500 patients across 17 countries.
Read moreInsomnia is a driver of suicide, and particularly people with severe insomnia may safely benefit from taking a sedative to help address their sleep problems as it reduces their suicidal thoughts, investigators report.
Read morePeople who received omega-3 fish oil supplements in randomized clinical trials had lower risks of heart attack and other cardiovascular disease (CVD) events compared with those who were given placebo.
Read moreFor the first time, prostate cancer has been treated based on the genetic makeup of the cancer, resulting in delayed disease progression, delayed time to pain progression, and potentially extending lives in patients with advanced, metastatic prostate cancer, reports a large phase 3 trial. This marks a significant advance for prostate cancer treatment, which has lagged behind other common cancers with regard to precision therapy, now the standard of care in breast, ovarian and lung cancers.
Read moreFrom 20 minutes or more to 10 seconds. Researchers from Intermountain Healthcare and Stanford University say 10 seconds is about how quickly a new system they studied that utilizes artificial intelligence took to accurately identify key findings in chest X-rays of patients in the emergency department suspected of having pneumonia.
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