Some parents pass on more mutations to their children than others

Everyone is a mutant but some are prone to diverge more than others, report scientists. A new study shows the number of mutations a child has compared to her parents varies dramatically with some people being born with twice as many as others, and that characteristic runs in families.

Read more

Discovery of how colorectal cancer drug works will help more patients

Some colorectal cancer patients with a certain gene mutation benefit from a chemotherapy drug called cetuximab, although the mechanism of how this drug worked was unknown. Scientists have combined computational biology with experimental investigations to discover, for the first time, the mechanism for why these patients respond to cetuximab, which will help doctors identify more effective, targeted treatment plans for people diagnosed with colorectal cancer.

Read more

Quality control in immune communication: Chaperones detect immature signaling molecules

The cells of our immune system constantly communicate with one another by exchanging complex protein molecules. A team has now revealed how dedicated cellular control proteins, referred to as chaperones, detect immature immune signaling proteins and prevent them from leaving the cell.

Read more

Chronic insomnia can be cured in cancer survivors with a basic sleep education class

Investigators report that a single-session sleep education program for survivors can cure insomnia in many participants, and that those who don't benefit from this approach are often helped by a more extensive, but still modest, three-session program.

Read more