A new study indicates a way for cancer immunotherapy to spur a more robust immune response. Such knowledge could lead to the development of better cancer vaccines and more effective immunotherapy drugs called checkpoint inhibitors.
Read moreNew research shows that lactate, an end product of metabolism, changes the function of an immune cell known as a macrophage, thereby rewiring it to behave differently.
Read moreA study in humans and mice demonstrated that a fetus has its own microbiome, or communities of bacteria living in the gut, which are known to play important roles in the immune system and metabolism. Researchers also confirmed that the fetal microbiome is transmitted from the mother.
Read moreVibrio parahaemolyticus can be found in the tidal zones in estuarine areas. The marine bacterium causes acute gastroenteritis in humans and is the leading cause for seafood borne illnesses in the world. Researchers have now identified specialized "adventurer" cells that ensure the bacterium's dissemination and prevalence. Their new findings are an important basis for the future management of the disease.
Read moreNew research provides insights into how the body can protect itself from immunopathology during flu.
Read moreTissue patterning is an important process during embryo formation, which ensures that groups of cells are arranged in an appropriate manner that allows them to function properly.
Read moreNew research into the mechanics of cellular sleep and shutdown could shed light on the aging process and how to potentially intervene.
Read moreNeural crest cells have been thought to originate in the ectoderm, the outermost of the three germ layers formed in the earliest stages of embryonic development. But their capacity to form derivatives like bone and tooth-forming cells defies fundamental concepts in developmental and stem cell biology. A research team has found a solution to this mystery by demonstrating an earlier origin of the neural crest in chick embryos.
Read moreHuman-made toxic chemicals that linger indefinitely in the environment disrupt the performance of critical helper cells in the mouse brain, leading to impaired function over long-term exposures.
Read moreA phase 2 clinical trial using a new technology show it is possible to induce immune tolerance to gluten in individuals with celiac disease. After treatment with the technology, the patients were able to eat gluten with a substantial reduction in inflammation.
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