Illumination of abnormal neuronal activities caused by myelin impairment

The neural circuit basis for motor learning tasks when myelination is impaired has been illuminated for the first time. Researchers also succeeded in compensating for the impaired motor learning process by pairing appropriate actions with brain photo-simulation to promote synchronization of neuronal activities. This could contribute to future treatments for neurological and psychiatric diseases in which white matter function is impaired.

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Brain mechanisms have potential to block arthritis pain

Because pain is a complex condition, treating it efficiently continues to pose challenge for physicians. Past pain research typically has focused upon the spinal cord or the peripheral areas of the nervous system located outside the spinal cord and brain. However, a research team recently investigated how some mechanisms in the brain contribute to pain.

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New diagnostic criteria may enable earlier detection of cognitive impairment in women

Study finds when verbal memory test cut-offs were tailored to patient sex, more female patients and fewer male patients were considered to have amnesic mild cognitive impairment. This could change the way aMCI diagnoses are determined and make it easier to catch the condition in its early stages.

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New method visualizes groups of neurons as they compute

Using a fluorescent probe that lights up when brain cells are electrically active, researchers found they can image the activity of many neurons at once, in mice brains. The technique could allow neuroscientists to analyze circuits within the brain and link them to specific behaviors.

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