Synthetic cells capture and reveal hidden messages of the immune system

New research is highly relevant to how antibodies are made in response to infections, vaccines and in autoimmunity due to the its analysis of a signal that is associated with hyper IgM syndrome, a genetic deficiency of CD40 ligand (CD40L) that results in profound immunodeficiency.

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How microtubules branch in new directions, a first look in animals

Cell biologists say they have, for the first time, directly observed and recorded in animal cells a pathway called branching microtubule nucleation, a mechanism in cell division that had been imaged in cellular extracts and plant cells but not directly observed in animal cells.

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Few people with peanut allergy tolerate peanut after stopping oral immunotherapy

Studies have shown that peanut oral immunotherapy (OIT) — ingesting small, controlled amounts of peanut protein — can desensitize adults and children and prevent allergic reactions, but the optimal duration and dose is unknown. In a study that followed participants after successful OIT, discontinuing OIT or continuing OIT at a reduced dose led to a decline in its protective effects. The study also found that blood tests administered before OIT could predict the success of therapy.

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