By scanning whole brains of Alzheimer's model mice from an early age, researchers were able to precisely trace the terrible march of amyloid plaques from deep brain structures outward along specific circuits. They also showed that plaque density in a key region in humans scales with disease stage.
Read moreA team of biomedical engineers are developing a therapy which shows early indications it can protect neurons and stimulate the regrowth of blood vessels in damaged tissue.
Read moreTwo new studies report progress in using stem cells to develop new therapies for Pelizaeus-Merzbacher disease (PMD), a rare genetic condition affecting boys that can be fatal before 10 years of age.
Read moreDistinct patterns of electrical activity in the sleeping brain may influence whether we remember or forget what we learned the previous day, according to a new study. The scientists were able to influence how well rats learned a new skill by tweaking these brainwaves while animals slept, suggesting potential future applications in boosting human memory or forgetting traumatic experiences, the researchers say.
Read moreResearchers have discovered a molecular process that controls the rate at which nerves grow both during embryonic development and recovery from injury throughout life.
Read moreResearchers have uncovered sex-based differences in the development of the hippocampus and amygdala. These brain areas have been implicated in the biology of several mental disorders that impact males and females differently. The findings may help researchers better understand sex-based differences in the emergence of mental disorders during adolescence and early adulthood.
Read moreA team of New Jersey stroke researchers has linked recovery of reading and language competence with cerebral blood flow in the left reading network. Their findings may contribute to new approaches to identifying and treating reading deficits after stroke.
Read moreChemical engineers have developed the first molecular motor that enables an eight-shaped movement.
Read moreIn some forms of epilepsy, the function of certain ''brake cells'' in the brain is presumed to be disrupted. This may be one of the reasons why the electrical malfunction is able to spread from the point of origin across large parts of the brain. A current study points in this direction.
Read moreA new mechanism makes it possible to understand premature ageing in cells with asymmetrical cell division, as is the case with mother cells. Understanding this mechanism is useful for studying and, in the future, anticipating the development of ageing-related diseases, such as cancer and neurodegenerative processes.
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