How common genetic mutation drives cancer
A new, multicenter study has determined how a single mutation in splicing factor 3b subunit 1 (SF3B1), the most frequently mutated splicing factor gene, drives the formation of many cancers.
Read morePancreatic Cancer
Innovative pancreatic cancer treatment may rev up immune system
A research team reports that combining a type of radiation therapy with immunotherapy not only cures pancreatic cancer in mice, but appears to reprogram the immune system to create an 'immune memory' in the same way that a vaccine keeps the flu away. The result is that the combination treatment also destroyed pancreatic cells that had spread to the liver, a common site for metastatic disease.
Read moreLymphoma stage at diagnosis may predict when and where new cancer forms
A new study shows the stage at which lymphoma is originally diagnosed impacts the types of second cancers that may form after treatment.
Read moreScientists have identified the presence of cancer-suppressing cells in pancreatic cancer
Researchers have identified cells containing a protein called Meflin that has a role in restraining the progression of pancreatic cancer. They have also shown that cancer progression can be controlled by artificially increasing the amount of this protein in the cells.
Read moreCancer data provide insights into occurrence, overdiagnosis, and treatment advances
Investigators analyzed 40 years of cancer burden data and examined patterns of incidence and mortality for various cancers, finding examples for which incidence and mortality moved in concert and examples where discordance in incidence and mortality indicate that overdiagnosis may be at play.
Read moreFungal invasion of pancreas creates cancer risk
Certain fungi move from the gut to the pancreas, expand their population more than a thousand-fold, and encourage pancreatic cancer growth, a new study finds.
Read moreNew approach to pain treatment in diseases of the pancreas
One of the worst symptoms associated with inflammation or cancer of the pancreas is severe chronic pain. Pancreatic pain is difficult to treat, because many painkillers prove ineffective in pancreatic patients. In a recent study, medical researchers discovered the cause of this phenomenon for the first time: a particular neuroenzyme in the body is present in the nerves of the organ in high concentrations.
Read moreDiscovery of new source of cancer antigens may expand cancer vaccine capabilities
Scientists have found a common, new source of tumor mutations that could offer three levels of therapy with a cancer vaccine: 1) a broadly protective, or pan-cancer vaccine 2) cancer-type specific vaccines (e.g. breast vs. pancreatic), 3) personalized cancer vaccines based on mutations unique to an individual.
Read moreWhole genome sequencing could enable personalized cancer treatment
Whole genome sequencing of tumour cells could help predict the prognosis of a patient's cancer and offer clues to identify the most effective treatment, suggests an international study.
Read moreNew blood test capable of detecting multiple types of cancer
A new blood test in development has shown ability to screen for numerous types of cancer with a high degree of accuracy, a trial of the test shows.
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