New studies show that a bacterial molecule, peptidoglycan, is present in the brain and fluctuates with sleep patterns. This challenges the idea that sleep is solely brain-driven, instead suggesting it’s a collaborative process between our bodies and microbiomes. The theory links microbes not only to sleep but also to cognition, appetite, and behavior, pointing to a profound evolutionary relationship.
Read moreGifted dogs can categorize toys by function, not just appearance. In playful at-home tests, they linked labels like “fetch” and “pull” to toys—even ones they’d never seen before. The findings hint that dogs form mental concepts of objects, much like humans, pointing to deeper cognitive abilities.
Read moreResearchers found that pancreatic pre-cancer cells mimic dementia by forming clumps of proteins due to faulty recycling processes. These insights could shed light on why pancreatic cancer develops so aggressively and why it is difficult to treat. By studying overlaps with neurological diseases, scientists hope to identify new strategies for prevention and treatment.
Read moreA new study has revealed that TSPO, a protein linked to brain inflammation, rises long before Alzheimer’s symptoms appear. Researchers tracked the protein in genetically engineered mice and confirmed the results in human brain tissue from Colombian families with a known Alzheimer’s mutation. They found unusually high levels of TSPO in microglia clustered around plaques, particularly in women. This discovery not only deepens our understanding of the disease but also sparks the possibility of using TSPO to detect and treat Alzheimer’s far earlier than ever before.
Read moreMicroplastics have been detected in human blood, brain tissue, and even bones, where they may weaken skeletal structure and accelerate cell aging. Recent studies suggest that these particles could worsen metabolic bone diseases like osteoporosis, a risk that’s especially concerning as fractures are projected to rise sharply in the coming decades.
Read morePlastic particles from everyday items like Styrofoam cups and take-out containers are finding their way into the brain, where they may trigger Alzheimer’s-like symptoms. New research shows that mice carrying the Alzheimer’s-linked APOE4 gene who consumed microplastics exhibited sex-dependent cognitive decline, mirroring the differences seen in human patients.
Read moreRogue DNA rings known as ecDNA may hold the key to cracking glioblastoma’s deadly resilience. Emerging before tumors even form, they could offer scientists a crucial early-warning system and a chance to intervene before the disease becomes untreatable.
Read moreAnimal models can serve as gateways for understanding many human communication disorders, but a new study suggests that the established practice of socially isolating mice for such purposes might actually make them poor research models for humans, and a simple shift to a more realistic social environment could greatly improve the utility of the future studies.
Read moreLocal people in the Nepal Himalayas value snow leopards as much for the potential personal benefits they gain from the animals' conservation as they do for the intrinsic value of this charismatic species.
Read moreGame theory has historically studied cooperation and hierarchy, and has sought to explain why individuals cooperate, even though they might be better off not to do so. Researchers now use a specialized graph to map a social network of cooperators and their neighbors; they discovered cooperators can attract more neighbors to follow their behaviors and are more likely to become leaders, indicating different learning patterns exist between cooperators and defectors.
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