Patients with mesothelioma may gain similar benefit from immunotherapy as chemotherapy, and good responders may provide important clues to novel treatment for the thousands of new cases each year. New data highlight the need to understand the biological mechanisms whereby mesothelioma, which is incurable, adapts to immunotherapy in some patients but not in others, resulting in variations in treatment response.
Read moreNew research found that oncogene SET/TAF1, which was found to be a proto-oncogene of acute myeloid leukemia (AML), contributes to proper chromosome partitioning as a tension sensor. Additionally, abnormal SET protein disrupts tension sensor system at the centromere, leading to missegregation of the chromosomes and thereby cancer. These findings may lead to a discovery for a new kind of leukemia treatment.
Read moreResearchers have found that steps measured through a step tracker worn on the wrist can be used to estimate exercise capacity and determine the health status of patients, rather than the standardized 6-minute walk distance test, which is usually conducted in a clinical setting.
Read moreAfrican Americans suffer asthma more often and more severely than Caucasian patients. However, clinical trials that have shaped treatment guidelines have included few African Americans. A new report demonstrates a shortcoming of that history. Researchers report that African American children respond differently than African American adults and Caucasian adults and children to step-up therapies for inadequately controlled asthma.
Read moreIn a new study, researchers reveal that a lifelong dietary regimen of choline holds the potential to prevent Alzheimer's disease (AD).
Read moreMen with prostate cancer can be spared radiotherapy after surgery, according to new results. The study answers a longstanding question about whether the benefits of radiotherapy after surgery outweigh the side-effects.
Read moreWhile blood samples can reliably identify people with a low risk of developing severe liver disease, better methods are needed in primary care for identifying people in most need of care.
Read moreIn a study of 115,803 individuals, the authors have identified 233 sites or loci in the human genome that contribute to the onset of MS. This is the largest study to date in MS.
Read moreFor the last 60 million years, fungus-growing ants have farmed fungi for food. In their cultivation of those fungi, they've successfully relied on bacteria-produced antimicrobial ingredients to protect their crops from other species of parasitic fungi. Now, researchers say they are looking to these ants to find new ways to stop or slow the evolution of antibiotic resistance that now presents a threat to modern medicine.
Read moreThe Global Program to Eliminate Lymphatic Filariasis delivers mass drug administration to 500 million people each year, and adverse events are common following treatment. Now, researchers have reported that certain changes in gene expression are associated with these adverse events.
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