Food science and human nutrition researchers are interested in the potential of inflammation-fighting compounds found in the silverskin and husk of coffee beans, not only for their benefits in alleviating chronic disease, but also in adding value to would-be 'waste' products from the coffee processing industry.
Read moreThe researchers recruited healthy older participants to two groups according to their history of tea drinking frequency and investigated both functional and structural networks to reveal the role of tea drinking on brain organization.
Read moreFor years, scientists have used cells grown in petri dishes to study the metabolic processes that fuel the immune system. But a new report suggests looking outside the dish and into living organisms gives a drastically different view of the way immune cells process and use energy.
Read moreThe first comprehensive look at the immune system of the fetal gut shows that it is far more developed before birth, and could help develop new maternal vaccines and reveal if we are predisposed to autoimmune diseases before birth.
Read moreTendon tears, both to the rotator cuff and Achilles heel, are common injuries, especially in aged individuals. Painful and disabling, they can adversely impact quality of life. New approaches are required to help patients suffering from chronic tendon injuries. A novel study identified mediators that promote resolution of inflammation as potential new therapeutics to push chronically injured tendons down an inflammation-resolving pathway.
Read moreIn a world first, scientists have created the human developmental liver cell atlas that provides crucial insights into how the blood and immune systems develop in the fetus. It maps changes in the cellular landscape of the developing liver between the first and second trimesters of pregnancy, including how stem cells from the liver seed other tissues to support the high demand for oxygen needed for growth.
Read moreThe fight against liver disease could be helped by the discovery of cells that cause liver scarring.
Read moreAn international team of researchers identifies the genetic basis for the hypervirulence of a Listeria strain that can cause severe infections.
Read moreIn Germany alone there are around 400,000 patients who suffer from chronic inflammatory bowel diseases. For the first time, researchers have discovered that dysfunctions in blood vessels play a significant role in the development of such diseases. In experimental model systems, the progression of the disease slowed down significantly by eliminating these dysfunctions.
Read moreA research team reports that combining a type of radiation therapy with immunotherapy not only cures pancreatic cancer in mice, but appears to reprogram the immune system to create an 'immune memory' in the same way that a vaccine keeps the flu away. The result is that the combination treatment also destroyed pancreatic cells that had spread to the liver, a common site for metastatic disease.
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