Leukemia drug shows promise for treating a childhood brain cancer
Researchers describe a new use of leukemia drug, nilotinib, to treat a subtype of medulloblastoma, a deadly pediatric brain cancer.
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Novel regulator of mitochondrial cell death reveals a promising target for cancer therapy
Researchers have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target.
Read moreEvidence underpinning approval of new cancer drugs raises questions
Around half of trials that supported new cancer drug approvals in Europe between 2014 and 2016 were judged to be at high risk of bias, which indicates that treatment effects might have been exaggerated, concludes a new study.
Read moreImaging reveals new results from landmark stem cell trial for stroke
Researchers reported today that bone marrow cells used to treat ischemic stroke in an expanded Phase I trial were not only safe and feasible, but also resulted in enhanced recovery compared to a matched historical control group.
Read moreNew drug target in fight against cancer
Researchers have discovered how a cancer-linked version of the protein mitoNEET can close voltage-dependent anion channels (VDAC), primary gateways in the outer surface of mitochondria. The researchers detail how mitoNEET regulates VDAC, and they show that the interactions between the two proteins could be disrupted by a drug that targets VDAC.
Read moreCancer cells turn to cannibalism to survive chemotherapy, study suggests
Researchers have discovered that some cancer cells survive chemotherapy by eating their neighboring tumor cells. The study suggests that this act of cannibalism provides these cancer cells with the energy they need to stay alive and initiate tumor relapse after the course of treatment is completed.
Read morePsoriasis drug target offers potential for osteosarcoma
A treatment for psoriasis could be repurposed to treat a rare but aggressive form of youth cancer, new findings suggest.
Read moreNovel approach to ultrasound raises possibility of new medical applications
A new ultrasound technique provides a non-invasive way of assessing bone structure on the microscale. Researchers hope to fine-tune the technique for use in assessing osteoporosis risk and treatment.
Read moreNew way to target cancer's diversity and evolution
Scientists have revealed close-up details of a vital molecule involved in the mix and match of genetic information within cells — opening up the potential to target proteins of this family to combat cancer's diversity and evolution.
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