Popular sugar substitute linked to brain cell damage and stroke risk

Erythritol, a widely used sugar substitute found in many low-carb and sugar-free products, may not be as harmless as once believed. New research from the University of Colorado Boulder reveals that even small amounts of erythritol can harm brain blood vessel cells, promoting constriction, clotting, and inflammation—all of which may raise the risk of stroke.

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Young adults with PTSD may have a higher risk of stroke in middle age

Young adults who develop PTSD after a traumatic event (e.g., gun violence, sexual assault, military combat or natural disaster) may be more likely to experience a transient ischemic attack (TIA) or major stroke event by middle age. This nationwide study of more than 1.1 million adults showed that PTSD may be a potent risk factor for developing stroke at a young age.

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Cutting-edge neuroethics with ground-breaking neurotechnologies

Scientists are developing powerful new devices and technologies to monitor and regulate brain activity. To ensure NIH keeps pace with rapid technological development and help clinicians and researchers ethically fit these new tools into practice, a new article highlights potential issues around and offers recommendations about clinical research with both invasive and noninvasive neural devices.

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Frontotemporal dementia is associated with alterations in immune system function

Recent research has revealed increased inflammatory activity in a subgroup of patients with frontotemporal dementia (FTD). Increased inflammation was associated with parkinsonism symptoms and more rapid disease progression. In addition, the results showed that cancer is rare in FTD, whereas some autoimmune diseases may be more common among FTD patients. These findings may indicate an overactive immune system in FTD.

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Dog ownership associated with longer life, especially among heart attack and stroke survivors


Dog ownership was associated with a 33% lower risk of early death for heart attack survivors living alone and 27% reduced risk of early death for stroke survivors living alone, compared to people who did not own a dog. Dog ownership was associated with a 24% reduced risk of all-cause mortality and a 31% lower risk of death by heart attack or stroke compared to non-owners.

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