Targeting deeply held values crucial for inspiring pro-environmental behavior

Given the alarming pace of climate change, it is increasingly important to understand what factors motivate people to take action – or not – on environmental issues. A recent study shows that deeply held values, which align closely with political leanings, can predict whether someone takes action to protect the environment.

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Acceptance and commitment therapy may ease fear of recurrence in cancer survivors

Researchers report that Acceptance and Commitment Therapy (ACT) shows significant promise for treating fear of cancer recurrence in women who have survived breast cancer. Fear that cancer may come back or progress is especially common in breast cancer survivors, with up to 70% reporting that the fear affects their daily life.

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Drug-light combo could offer control over CAR T-cell therapy

Bioengineers are a step closer to making CAR T-cell therapy safer, more precise and easy to control. They developed a system that allows them to select where and when CAR T cells get turned on so that they destroy cancer cells without harming normal cells. The system requires two 'keys' — the drug Tamoxifen and blue light — to activate CAR T cells to bind to their targets.

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Inactive receptor renders cancer immunotherapies ineffective

The aim of immunotherapies is to enable the immune system once again to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose. However, they are only effective in about one third of patients. Based on analysis of human tissue samples, a team has now discovered one reason why this is so: an inactive receptor in cancer cells prevents the drugs from reactivating the immune system.

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Muscadine grapes are affected by parasitic nematodes

Muscadines are also known for being hearty grapes, with a tough skin that protects them from many fungal diseases. Bunch grapes are highly susceptible to damage from plant-parasitic nematodes (PPNs), which affect their health, quality, production, and maintenance. Now we know that PPNs also affect muscadines.

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Creating miracles with polymeric fibers

Scientists are studying the fabrication of polymeric nanofibers and microfibers — very thin fibers made up of polymers. The fibers can be woven into textile-like structures but depending on the use, different fiber thicknesses may be necessary. To study the effects of various parameters on fiber fabrication, the researchers compared the characteristics of fibers created in different ways.

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Gene mutation in the chloride channel triggers rare high blood pressure syndrome

When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel. Researchers have now been able to show for the first time how the altered channels cause the disease.

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