New fluorescence method reveals signatures of individual microbes

Researchers have developed a new method that reveals the unique fluorescence patterns produced by individual cells in mixtures of bacteria, yeast and fungi. They combined confocal microscopy with micro-spectroscopy to determine the fluorescence signatures from different types of microbes. They trained machine learning systems to analyze the images and identify different individual cells and cell-types automatically, even those with very similar shapes and sizes.

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New method to purify cell types to high purity

Current biology research relies on the ability to purify cell types using antibodies or transgenic constructs. However, antibody availability is often limited, and genetic manipulation is labor intensive or sometimes impossible. To date, no universal method exists to enrich for cell types without a priori knowledge of cell type markers. Here, we propose GateID, a computational method that combines single-cell transcriptomics with FACS index sorting to purify cell types using only native cellular properties.

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Using high energy density material in electrode design enhances lithium sulfur batteries

To develop higher capacity batteries, researchers have looked to lithium sulfur batteries because of sulfur's high theoretical capacity and energy density. But there are still several problems to solve before they can be put into practical applications. The biggest is the shuttling effect that occurs during cycling. To solve this problem and improve lithium sulfur battery performance, the researchers created a sandwich-structured electrode using a novel material that traps polysulfides and increases the reaction kinetics.

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A new concept could make more environmentally friendly batteries possible

A new concept for an aluminium battery has twice the energy density as previous versions, is made of abundant materials, and could lead to reduced production costs and environmental impact. The idea has potential for large scale applications, including storage of solar and wind energy.

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