Antibiotic resistance in food animals nearly tripled since 2000

Researchers report that the growing appetite for animal protein in low- to middle-income countries has resulted in a smorgasbord of antibiotic consumption for livestock that has nearly tripled the occurrence of antibiotic resistance in disease-causing bacteria between 2000 and 2018. The researchers found that antibiotic resistance in livestock was most widespread in China and India, with Brazil and Kenya emerging as new hotspots.

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From sleeping cell to assassin — how immune cells work

Scientists have carried out one of the most comprehensive studies into how immune cells sense and respond to their environment to fight infection and destroy tumors. The research team said the results provide important insights into how immune responses might be manipulated for the treatment of autoimmune diseases and cancer.

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Analysis of HIV-1B in Indonesia illuminates transmission dynamics of the virus

Research into the molecular phylogeny (evolutionary history) of the HIV-1B virus in Indonesia has succeeded in illuminating the transmission period and routes for three clades (main branches of the virus). This includes a clade thought to be unique to Indonesia, as well as clades that spread from Thailand, Europe and America in the 1970s and 1980s.

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Engineered viruses could fight drug resistance

Biological engineers can program bacteriophages to kill different strains of E. coli by making mutations in the protein that the viruses use to bind to host cells. These engineered phages are less likely to provoke resistance in bacteria, and could help to overcome antibiotic resistance.

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Most kidney transplants between people with HIV have long-term success

People living with HIV who received kidney transplants from deceased donors with HIV had high rates of overall survival and kidney graft survival after five years, according to an observational study. The investigators followed 51 study participants with HIV who received kidney transplants from deceased donors with HIV in South Africa.

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How AIDS pathogens multiply in the body

Scientists have now succeeded in using high-resolution imaging to make visible to the millisecond how the HI virus spreads between living cells and which molecules it requires for this purpose. The researchers provide direct proof for the first time that the AIDS pathogen creates a certain lipid environment for replication.

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