Cambridge scientists created a gel that could end arthritis pain

Cambridge scientists have created a breakthrough material that can sense tiny chemical changes in the body, such as the increased acidity during an arthritis flare-up, and release drugs exactly when and where they’re needed. By mimicking cartilage while delivering medication, this smart gel could ease pain, reduce side effects, and provide continuous treatment for millions of arthritis sufferers.

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This high-sugar fruit may actually lower diabetes risk

Mangos, often dismissed as too sugary, may hold hidden benefits for those at risk of diabetes. A George Mason University study found that daily mango eaters showed better blood sugar control and less body fat than those eating a lower-sugar snack. The results suggest that it’s not just sugar levels, but how the sugar is packaged in whole foods, that matters.

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Scientists reveal pill that helps shed 20% of body weight

A massive international study has shown that the experimental oral obesity drug orforglipron can help patients shed over 10% of their body weight, with nearly one in five losing 20% or more. Unlike most GLP-1 agonists that require injections, orforglipron comes as a once-daily pill, potentially making weight-loss treatment more accessible.

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AI-powered smart bandage heals wounds 25% faster

A new wearable device, a-Heal, combines AI, imaging, and bioelectronics to speed up wound recovery. It continuously monitors wounds, diagnoses healing stages, and applies personalized treatments like medicine or electric fields. Preclinical tests showed healing about 25% faster than standard care, highlighting potential for chronic wound therapy.

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Tylenol in pregnancy linked to higher autism risk, Harvard scientists report

Researchers reviewing 46 studies found evidence linking prenatal acetaminophen (Tylenol) exposure with higher risks of autism and ADHD. The FDA has since urged caution, echoing scientists’ advice that the drug be used only at the lowest effective dose and shortest duration. While important for managing fever and pain in pregnancy, prolonged use may pose risks to fetal development. Experts stress careful medical oversight and further investigation.

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When cancer cells feel squeezed, they become more dangerous

New research shows that cancer cells don’t just grow; they adapt when stressed. When squeezed inside tissues, they transform into more invasive, drug-resistant versions of themselves. A protein called HMGB2 helps flip this dangerous switch, giving the cells new powers to escape. The findings reveal how the tumor’s environment itself can drive cancer’s deadly flexibility.

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Why alcohol blocks the liver from healing, even after you quit

Alcohol doesn’t just damage the liver — it locks its cells in a strange “in-between” state that prevents them from healing. Even after someone quits drinking, liver cells often get stuck, unable to function normally or regenerate. Scientists have now traced this problem to runaway inflammation, which scrambles the cell’s instructions and silences a key helper protein. By blocking these inflammatory signals in lab tests, they were able to restore the liver’s healing ability — a finding that could point to new treatments beyond transplants.

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This stunning X-ray advance could help detect cancer earlier

Sandia scientists developed a new type of X-ray that uses patterned multi-metal targets to create colorized, high-resolution images. The technology promises sharper scans, better material detection, and transformative applications in security, manufacturing, and medicine.

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Simple therapies outperform drugs for knee arthritis pain relief

A sweeping analysis of nearly 10,000 patients reveals that knee braces, hydrotherapy, and exercise stand out as the most effective non-drug therapies for knee osteoarthritis. Unlike common pain medications that carry risks, these low-cost and accessible options reduce pain, improve mobility, and could shift treatment guidelines toward safer, drug-free approaches.

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Scientists uncover exercise’s secret hunger-busting molecule

Scientists have uncovered how exercise suppresses appetite through a surprising molecular pathway. A compound called Lac-Phe, produced during intense workouts, directly quiets hunger neurons in the brain while boosting appetite-suppressing ones, causing mice to eat less without side effects. This discovery reveals a natural mechanism linking physical activity and reduced hunger, paving the way for new obesity treatments.

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