Everyone is a mutant but some are prone to diverge more than others, report scientists. A new study shows the number of mutations a child has compared to her parents varies dramatically with some people being born with twice as many as others, and that characteristic runs in families.
Read moreSome colorectal cancer patients with a certain gene mutation benefit from a chemotherapy drug called cetuximab, although the mechanism of how this drug worked was unknown. Scientists have combined computational biology with experimental investigations to discover, for the first time, the mechanism for why these patients respond to cetuximab, which will help doctors identify more effective, targeted treatment plans for people diagnosed with colorectal cancer.
Read moreCells that become senescent irrevocably stop dividing under stress, spewing out a mix of inflammatory proteins that lead to chronic inflammation as more and more of the cells accumulate over time. Researchers have identified 44 specific senescence-associated proteins that are involved in blood clotting, marking the first time that cellular senescence has been associated with age-related blood clots.
Read moreA new treatment method promises to speed up gene therapy research and could bring new, patient friendly cancer treatments to market faster.
Read moreSome of the genes that predict the risk of high cholesterol don't apply to people from Uganda the same as they do in European populations, finds a new study.
Read moreA new clinical trial found a cost-effective generic drug works just as well as a more expensive drug in preserving heart function in boys with Duchenne muscular dystrophy.
Read moreA recent analysis from Canada found that information on health-related quality of life is often not collected for investigational cancer drugs or used to calculate the balance of costs and benefits of these drugs when they are submitted for reimbursement.
Read moreIn people with diabetes, fat mass index, not body mass index (BMI), is associated with a higher risk of cardiovascular events, according to new research.
Read moreUNC researchers have created an injectable multi-drug delivery system that is removable, biodegradable and effective for up to a year in some cases. The author says the ability to administer multiple drugs with this implant is an important advancement in this research.
Read moreA research team has examined the interplay between genetics, cardiovascular disease and educational attainment in a major population study. Genetic variants which had been linked to educational attainment in other studies were observed in the subjects. The researchers found that these variants also had implications for a more health-conscious lifestyle and thus a lower risk of cardiovascular disease – in some cases regardless of the level of education.
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