Why do some people stay protected after vaccination while others quickly lose immunity? Researchers in Japan tracked over 2,500 people for 18 months and found four distinct immune response patterns. The so-called “rapid-decliners” looked strong at first but lost antibodies quickly, leaving them more vulnerable to infection.
Read moreScientists at the University of Geneva have created the first detailed catalogue of gut bacteria at the subspecies level, unlocking powerful new ways to detect colorectal cancer. By applying machine learning to stool samples, they achieved a 90% detection rate—nearly matching colonoscopies, but with far less cost and discomfort. This breakthrough could revolutionize early cancer screening, helping catch the disease before it advances.
Read moreRogue DNA rings known as ecDNA may hold the key to cracking glioblastoma’s deadly resilience. Emerging before tumors even form, they could offer scientists a crucial early-warning system and a chance to intervene before the disease becomes untreatable.
Read moreResearchers have discovered in mice how one of the few genes definitively linked to schizophrenia, called SETD1A, likely confers risk for the illness. Mice genetically engineered to lack a functioning version of the enzyme-coding gene showed abnormalities in working memory, mimicking those commonly seen in patients. Restoring the gene's function corrected the working memory deficit and counteracting its deficiency also repaired neuronal circuit deficits in adult mice — suggesting clues for potential treatment strategies.
Read moreA multicenter randomized clinical trial evaluating a new artificial pancreas system — which automatically monitors and regulates blood glucose levels — has found that the new system was more effective than existing treatments at controlling blood glucose levels in people with type 1 diabetes.
Read moreAs more and more youth use electronic cigarettes, combined with research showing the health consequences of vaping — including nicotine addiction — researchers found that non-menthol flavors attract youth and adults to use e-cigarettes and that the use of flavored e-cigarettes contributes to multiple pathways linked to higher e-cigarette use among youth.
Read moreHepatic insulin resistance, caused by diets high in sugar and fat, can lead to type 2 diabetes. Researchers found that the Elovl6 gene plays a key role in hepatic insulin resistance. Deleting Elov6 in liver cells causes a rise in a specific ceramide lipid that protects mice from hepatic insulin resistance due to excessive dietary sugar. The findings could help efforts to find a targeted treatment for the condition.
Read moreIn an effort to help identify skeletal remains of Thai descent, researchers have found that examining the distal humerus (elbow) bone is superior to previous techniques that were developed for identifying sex in a non-Asian population.
Read moreResearchers analyzed national data on the prevalence of diabetes and the number of internal medicine specialists in each U.S. state. They found that cardiologists were the highest represented specialists and conclude that they are well positioned to be integral members of a patient's care team.
Read moreWomen with an aggressive, less-common type of breast cancer, known as triple-negative, versus a more common form of the disease, could be differentiated from each other by a panel of 17 small RNA molecules that are directly influenced by genetic alterations typically found in cancer cells.
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