A recent analysis from Canada found that information on health-related quality of life is often not collected for investigational cancer drugs or used to calculate the balance of costs and benefits of these drugs when they are submitted for reimbursement.
Read moreUNC researchers have created an injectable multi-drug delivery system that is removable, biodegradable and effective for up to a year in some cases. The author says the ability to administer multiple drugs with this implant is an important advancement in this research.
Read moreThe first extensively drug-resistant (XDR) strains of Salmonella Typhimurium, a pathogen which is responsible for millions of bloodstream infections per year in sub-Saharan Africa, have been identified in the Democratic Republic of Congo (DRC). Drug-resistance has increased in successive groups of S. Typhimurium over time. These new strains are resistant to all but one of the commonly available drugs in the DRC, with one sample showing reduced susceptibility to this final antibiotic.
Read moreA molecule once designed to cure the skin disease psoriasis appears to be particularly effective against malaria. The antimalarial properties were revealed thanks to one researcher's inspired hunch when the psoriasis drug discovery program came to a dead end. The candidate drug offers considerable potential for combating this infectious disease.
Read moreThough research shows that medication-assisted treatment can help people who are addicted to opioids, the three drugs approved by the Food and Drug Administration (FDA) are underused, according to a review of current medical data on opioid addiction in the U.S.
Read moreAround half of trials that supported new cancer drug approvals in Europe between 2014 and 2016 were judged to be at high risk of bias, which indicates that treatment effects might have been exaggerated, concludes a new study.
Read moreModifying a class of molecules originally developed to treat the skin disease psoriasis could lead to a new malaria drug that is effective against malaria parasites resistant to currently available drugs.
Read moreBabies born vaginally have different gut bacteria — their microbiome — than those delivered by caesarean, research has shown. Scientists discovered that whereas vaginally born babies got most of their gut bacteria from their mother, caesarean babies instead had more bacteria associated with hospital environments in their guts. It isn't known if these differences at birth will have any effect on later health.
Read moreA minority of people who use illicit opioids indicated a preference for fentanyl, the super-potent synthetic opioid that accounts for much of the recent rise in US overdose deaths, according to a new study.
Read moreProteins keep our organs functioning, regulate our cells and are the targets for medications that treat a number of diseases, including cancers and neurological diseases. Proteins need to move in order to function. But, because the technology they used to watch proteins doesn't allow it, scientists still know very little about such motions at speeds slower than a nanosecond. That changed last month.
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