Three-person DNA IVF stops inherited disease—eight healthy babies born in UK first

In a groundbreaking UK first, eight healthy babies have been born using an IVF technique that includes DNA from three people—two parents and a female donor. The process, known as pronuclear transfer, was designed to prevent the inheritance of devastating mitochondrial diseases passed down through the mother’s DNA. The early results are highly promising: all the babies are developing normally, and the disease-causing mutations are undetectable or present at levels too low to cause harm. For families once haunted by genetic risk, this science offers more than treatment—it offers transformation.

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Society is rejecting facts; medical researchers can help

Anecdotes, fake news and social media have created a skeptical and misinformed public who is rejecting the facts. A commentary says that medical researchers must help the public understand the rigorous process of science and help them to discern an anecdote from peer-reviewed scientific results. The best way to do this? By continuing to ensure integrity, rigor, reproducibility and replication of their science and to earn the public's trust by being morally responsible and completely free of any influences.

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Beyond the 'replication crisis,' does research face an 'inference crisis'?

For the past decade, social scientists have been unpacking a 'replication crisis' that has revealed how findings of an alarming number of scientific studies are difficult or impossible to repeat. Efforts are underway to improve the reliability of findings, but cognitive psychology researchers say that not enough attention has been paid to the validity of theoretical inferences made from research findings.

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New CEOs can raise their social game to keep their jobs

A new study shows that two key factors can make freshly appointed CEOs more vulnerable and raise the odds they'll get fired. The job security of a new CEO tends to suffer when the stock market reacts badly or when the previous CEO stays on as board chair, according to the study. But the study found that the new CEO can overcome these challenges with what researchers call ''social influence behaviors.''

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Mounting brain organoid research reignites ethical debate

As research involving the transplantation of human 'mini-brains' — known as brain organoids — into animals to study disease continues to expand, so do the ethical debates around the practice. A new article seeks to clarify the abilities of brain organoids and suggests an ethical framework that better defines and contextualizes these organoids and establishes thresholds for their use.

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