Scientists have uncovered how exercise suppresses appetite through a surprising molecular pathway. A compound called Lac-Phe, produced during intense workouts, directly quiets hunger neurons in the brain while boosting appetite-suppressing ones, causing mice to eat less without side effects. This discovery reveals a natural mechanism linking physical activity and reduced hunger, paving the way for new obesity treatments.
Read moreCHESS thin-film materials nearly double refrigeration efficiency compared to traditional methods. Scalable and versatile, they promise applications from household cooling to space exploration.
Read moreNew research reveals lymphoma can directly accelerate aging in the immune system and vital organs, independent of treatments like chemotherapy. The changes, sometimes reversible, highlight a hidden dimension of cancer—and possible new paths for intervention.
Read moreDespite strong evidence that salt substitutes can safely lower sodium intake and reduce high blood pressure, very few Americans use them. A new analysis of nearly 20 years of national health data found that usage peaked at just over 5% and then declined, even among those with hypertension. Researchers say this represents a major missed opportunity to improve heart health, especially since salt substitutes are inexpensive and effective.
Read moreFor decades, scientists have puzzled over why smoking makes Crohn’s disease worse but seems to protect people from ulcerative colitis. Now, researchers at RIKEN have discovered that smoking creates metabolites like hydroquinone that allow mouth bacteria—especially Streptococcus mitis—to settle in the gut. These bacteria spark an immune response that reduces inflammation in colitis but worsens Crohn’s. The findings open the door to new therapies using probiotics or targeted compounds that mimic smoking’s protective effects without its deadly risks.
Read moreFrom the wreck of the royal Danish-Norwegian flagship Gribshunden, archaeologists have uncovered a rare glimpse into the naval power of the late Middle Ages. This warship, lost in 1495, carried an arsenal of small guns designed for close-range combat, symbolizing the technological leap that allowed European nations to dominate the seas. More than just a vessel, it served as King Hans’ floating castle, projecting both diplomatic influence and military might.
Read moreA sweeping investigation has revealed widespread fraud in mathematics publishing, where commercial metrics and rankings have incentivized the mass production of meaningless or flawed papers. The study highlights shocking distortions—such as a university without a math department ranked as having the most top mathematicians—and the explosion of megajournals willing to publish anything for a fee.
Read moreEgg-eating worms living on Chesapeake Bay blue crabs may hold the key to smarter fishery management. Once thought to be a threat, these parasites actually serve as natural biomarkers that reveal when and how often female crabs reproduce. Researchers found the worms are surprisingly resilient to varying salinity levels, meaning they can track crab spawning across the Bay.
Read moreMayo Clinic scientists uncovered how excessive drinking triggers fatty liver disease by disrupting the enzyme VCP, which normally prevents harmful protein buildup on fat droplets in the liver. Alcohol blocks this protective process, allowing fat to accumulate and damage liver cells.
Read moreAlcohol-associated liver disease is becoming a massive health and economic burden, but researchers at UC San Diego may have uncovered a new way forward. They discovered that chronic alcohol use blocks a crucial protein that normally helps keep gut bacteria from leaking into the liver, worsening damage. Restoring this protein’s function, using drugs already in development, could not only reduce liver disease but also have implications for treating alcohol addiction itself.
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