Cells that become senescent irrevocably stop dividing under stress, spewing out a mix of inflammatory proteins that lead to chronic inflammation as more and more of the cells accumulate over time. Researchers have identified 44 specific senescence-associated proteins that are involved in blood clotting, marking the first time that cellular senescence has been associated with age-related blood clots.
Read moreResearchers have found a way to track the formation of soluble amyloid beta peptide aggregates in lab samples. The aggregates are implicated in the onset of Alzheimer's disease.
Read moreA child's desire to share becomes influenced by social norms around the age of 8, new research has revealed. The extensive study — conducted on eight diverse societies across the world — examined children and adults' behavior when asked to respond to a set of specific sharing tasks.
Read moreResearchers have used a technique called high-throughput mutagenesis to study Amyotrophic Lateral Sclerosis (ALS), with unexpected results. Results showed that aggregation of TDP-43 is not harmful but actually protects cells, changing our understanding of ALS and opening the door to radically new therapeutic approaches.
Read moreTo help physicians provide the highest quality patient-centered neurologic care, the American Academy of Neurology (AAN) is recommending physicians measure how frequently they complete annual assessments of people age 65 and older for thinking and memory problems.
Read moreIndividuals raised in families with higher socioeconomic status were more optimistic in midlife, and in turn, lived longer. Those who experienced more psychosocial stressors, such as parental death, frequent moves and harsh discipline, tended to encounter more stressful life events in midlife, and had greater risk of dying early.
Read moreThe potential positive, enabling, effects of walking modifications should also be considered when older people's functional ability declines.
Read moreNovel molecular mechanism may regulate microtubule stability, important for neuronal branching and potentially for nerve regeneration.
Read moreIn a small safety and feasibility clinical trial, researchers have demonstrated for the first time that senescent cells can be removed from the body using drugs termed 'senolytics.' The result was verified not only in analysis of blood but also in changes in skin and fat tissue senescent cell abundance.
Read moreExercising several times a week may delay brain deterioration in people at high risk for Alzheimer's disease, according to a new study that scientists say merits further research to establish whether fitness can affect the progression of dementia.
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