Candidate Ebola vaccine still effective when highly diluted, macaque study finds

A single dose of a highly diluted VSV-Ebola virus (EBOV) vaccine — approximately one-millionth of what is in the vaccine being used to help control the ongoing Ebola outbreak in the Democratic Republic of the Congo — remains fully protective against disease in experimentally infected monkeys, according to scientists. The investigators completed the dosage study using cynomolgus macaques and an updated vaccine component to match the EBOV Makona strain that circulated in West Africa from 2014-16.

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Newly discovered virus infects bald eagles across America

Researchers have discovered a previously unknown virus infecting nearly a third of America's bald eagle population. Scientists found the virus while searching for the cause of Wisconsin River Eagle Syndrome, an enigmatic disease endemic to bald eagles near the Lower Wisconsin River. The newly identified bald eagle hepacivirus, or BeHV, may contribute to the fatal disease, which causes eagles to stumble and have seizures.

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Scientists work toward a rapid point-of-care diagnostic test for Lyme disease

A study describes a new rapid assay for Lyme disease that could lead to a practical test for use by healthcare providers. The researchers found the assay, which uses several biomarkers to detect Lyme disease infection, was more sensitive than current laboratory-based tests when diagnosing Lyme disease early after suspected infection.

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Novel virus type may shed light on viral evolution

Viruses are non-living creatures, consisting of genetic material encased in a protein coat. Once the virus infects a living organism, it can replicate itself and continue on. But what happens if a virus lacks the proper tools to infect an organism? How can it propagate? Researchers have uncovered a novel virus that may help answer those questions.

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Muscadine grapes are affected by parasitic nematodes

Muscadines are also known for being hearty grapes, with a tough skin that protects them from many fungal diseases. Bunch grapes are highly susceptible to damage from plant-parasitic nematodes (PPNs), which affect their health, quality, production, and maintenance. Now we know that PPNs also affect muscadines.

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Sperm and egg cell 'immune response' protects koala DNA

Discovery of a type of immunity that protects koalas' DNA from viruses has importance for the survival of koalas and our fundamental understanding of evolution. A team of scientists are studying tissue samples from koalas to understand how a unique type of cell responds to retrovirus infections, which cause diseases such as chlamydia and cancer.

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New test diagnoses Lyme disease within 15 minutes

Current testing for Lyme disease, called the standard 2-tiered approach or the STT, involves running two complex assays (ELISA and western blot) to detect antibodies against the bacterium, and requires experienced personnel in a lab, and a few hours to carry out and interpret. Biomedical engineers have developed a rapid microfluidic test that can detect Lyme disease with similar performance as the STT in a much shorter time — 15 minutes.

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