A reliable clock for your microbiome

The microbiome is a treasure trove of information about human health and disease, but getting it to reveal its secrets is challenging. A new genetic 'repressilator' circuit acts like a clock that tracks how bacterial growth changes over time with single-cell precision. This tool allows scientists to noninvasively study the dynamics of the microbiome, and also unlocks the potential for complex, synthetic-biology-based diagnostics and therapeutics for the human gut.

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Scientists are decoding the genetic mechanisms of aging

Scientists describes the mechanisms by which longevity is regulated post-transcriptionally, or after a genetic blueprint has been transcribed from an organism's DNA. The identification of these mechanisms will serve as a road map for screening new, more specific drugs to prolong healthy lifespan. The laboratory focuses on research on regeneration and aging.

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Plant death may reveal genetic mechanisms underlying cell self-destruction

Hybrid plants, which produced by crossing two different types of parents, often die in conditions in which both parents would survive. Certain hybrid tobacco plants, for example, thrive at 36 degrees Celsius, but die at 28 degrees Celsius, which is the temperature at which both parents would thrive. Researchers have begun to unravel the molecular mechanisms by which hybrid tobacco plant cells meet their demise.

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