Sperm and egg cell 'immune response' protects koala DNA

Discovery of a type of immunity that protects koalas' DNA from viruses has importance for the survival of koalas and our fundamental understanding of evolution. A team of scientists are studying tissue samples from koalas to understand how a unique type of cell responds to retrovirus infections, which cause diseases such as chlamydia and cancer.

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Synthetic cells make long-distance calls

Synthetic biologists design transcriptional circuits that allow single-cell microbes to form networks that spur collective action, even in large communities. The work could lead to engineered microbes that treat conditions in gut microbiomes or communicate with bioelectronics.

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Unlocking the biochemical treasure chest within microbes

An international team of scientists has developed a genetic engineering tool that makes producing and analyzing microbial secondary metabolites — the basis for many important agricultural, industrial, and medical products — easier than ever before, and could even lead to breakthroughs in biomanufacturing.

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A reliable clock for your microbiome

The microbiome is a treasure trove of information about human health and disease, but getting it to reveal its secrets is challenging. A new genetic 'repressilator' circuit acts like a clock that tracks how bacterial growth changes over time with single-cell precision. This tool allows scientists to noninvasively study the dynamics of the microbiome, and also unlocks the potential for complex, synthetic-biology-based diagnostics and therapeutics for the human gut.

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