Swapping a single amino acid in a simple bacterial protein changes its structure and function, revealing the effects of complex gene evolution, finds a new study. The study — conducted using E. coli bacteria — can help researchers to better understand the evolution of transporter proteins and their role in drug resistance.
Read moreA research team has created a third approach to engineering proteins that uses deep learning to distill the fundamental features of proteins directly from their amino acid sequence without the need for additional information.
Read moreResearchers examined 31 peatlands across Britain, Ireland, Scandinavia and continental Europe to assess changes in peatland surface wetness during the last 2,000 years.
Read moreUsing high-throughput next-generation sequencing technology, a researcher found similarities in the folding tendencies among a family of RNA molecules called riboswitches, which play a pivotal role in gene expression.
Read moreCentromeres are the chromosomal domains at which the kinetochore, a protein complex required for the correct separation of chromosomes during mitosis and meiosis, is assembled. The incorporation of the histone variant CenH3 into centromeric nucleosomes is a prerequisite for the proper assembly and function of the kinetochore. A new study describes the chaperone protein NASPSIM3 and how it affects the depositioning of CenH3.
Read moreConsuming potato puree during prolonged exercise works just as well as a commercial carbohydrate gel in sustaining blood glucose levels and boosting performance in trained athletes, scientists report.
Read moreResearchers discover a new principle — how cells protect themselves from mitochondrial defects.
Read moreThe molecules of life are twisted. But how those familiar strands in DNA's double helix manage to replicate without being tangled up has been hard to decipher. A new perspective from physicists is helping unravel the mystery.
Read moreA recent study has revealed more details about how the synaptonemal complex performs its job, including some surprising subtleties in function.
Read moreA fast knee-jerk 'ballistic' escape response and a more considered 'delayed' escape response are mediated by distinct and parallel neuronal pathways in zebrafish, according to a new study.
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