There are many indications that fasting promotes longevity. In recent years, much attention has been devoted to so-called caloric restriction mimetics (CMRs), substances that simulate the health-promoting effects of fasting without the need of life-style change. A study reports the identification of a novel candidate CRM. The substance may prove useful in the further research for the treatment of age-related diseases.
Read moreThe once-rare 'fabella' bone has made a dramatic resurgence in human knees, but who's likely to have a fabella or two — and why?
Read moreResearchers used a grip-force test to analyze sensorimotor function in people with the FMR1 premutation, with the aim of determining FXTAS risk and severity.
Read moreNew research could help explain why memory in old age is much less flexible than in young adulthood. Through experiments in mice the researchers discovered that there were dramatic differences in how memories were stored in old age, compared to young adulthood.
Read moreScientists have isolated a natural chemical that acts as a potent kryptonite against parasitic worms that burrow through human skin and cause devastating health problems. Researchers now describe the successful characterization of this chemical, which could help in finding new ways to fight the neglected tropical disease schistosomiasis.
Read moreResearchers have found that carriers of the most common genetic variant that causes cystic fibrosis experience some symptoms similar to those of people with cystic fibrosis. These findings were enabled by large-scale genomic data made available just a few years ago.
Read moreProlonged exposure to blue light, such as that which emanates from your phone, computer and household fixtures, could be affecting your longevity, even if it's not shining in your eyes. New research suggests that the blue wavelengths produced by light-emitting diodes damage cells in the brain as well as retinas, according to a new study in a model organism.
Read moreA team of researchers has found evidence that metabolic dysfunction is a primary cause of Alzheimer's disease.
Read moreMutations in the gene that encodes a protein called ANT cause a variety of conditions, such as heart disease, but the underlying mechanism of how these mutations trigger disease has been unclear. Researchers discovered that ANT is critical for a quality control process called mitophagy — which helps to ensure the integrity of the mitochondria network — and found that mutations that lead to a defective quality control system cause heart disease.
Read moreResearchers discover that the activity of the nervous system might influence human longevity. Neural excitation linked to shorter life, while suppression of overactivity appears to extend life span. Protein REST, previously shown to protect aging brains from dementia and other diseases, emerges as a key player in molecular cascade related to aging. Findings suggest future avenues for intervention in diseases ranging from Alzheimer's to bipolar disorder.
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