Mushrooms evolved psychedelics twice, baffling scientists

Researchers found that magic mushrooms and fiber caps independently evolved different biochemical pathways to create psilocybin. This convergence shows nature’s ingenuity, but the reason why remains unknown—possibly predator deterrence. Beyond evolutionary mystery, the discovery provides new enzyme tools for biotech, with promising applications for producing psilocybin-based medicines.

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How dehydration secretly fuels anxiety and health problems

Not drinking enough water could intensify stress responses. Researchers found that under-hydrated individuals had cortisol levels more than 50% higher during stressful situations. Poor hydration didn’t make participants feel thirstier, but it did trigger biological signs of strain. Keeping a water bottle handy could help manage stress and safeguard health.

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Can meditation apps really reduce stress, anxiety, and insomnia?

Meditation apps are revolutionizing mental health, providing easy access to mindfulness practices and new opportunities for scientific research. With the help of wearables and AI, these tools can now deliver personalized training tailored to individual needs.

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Alcohol’s hidden shortcut lets gut bacteria wreck the liver

Alcohol-associated liver disease is becoming a massive health and economic burden, but researchers at UC San Diego may have uncovered a new way forward. They discovered that chronic alcohol use blocks a crucial protein that normally helps keep gut bacteria from leaking into the liver, worsening damage. Restoring this protein’s function, using drugs already in development, could not only reduce liver disease but also have implications for treating alcohol addiction itself.

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Doctors warn of a stealth opioid 20x more potent than fentanyl

Nitazenes, a powerful and largely hidden class of synthetic opioids, are quickly becoming a deadly factor in the overdose crisis. Over 20 times stronger than fentanyl, these drugs often go undetected on routine drug tests, making overdoses harder to diagnose and reverse. Cases from Tennessee reveal a disturbing pattern of fatalities, with nitazenes frequently mixed into counterfeit pills alongside fentanyl and methamphetamine.

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Doctors used music instead of medication—what they saw in dementia patients was remarkable

A groundbreaking pilot in NHS dementia wards is using live music therapy—called MELODIC—to ease patient distress without relying on drugs. Developed by researchers and clinicians with input from patients and families, this low-cost approach embeds music therapists directly into care teams. Early results show improved patient wellbeing and less disruptive behavior, sparking hope for wider NHS adoption.

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Schizophrenia risk gene linked to cognitive deficits in mice

Researchers have discovered in mice how one of the few genes definitively linked to schizophrenia, called SETD1A, likely confers risk for the illness. Mice genetically engineered to lack a functioning version of the enzyme-coding gene showed abnormalities in working memory, mimicking those commonly seen in patients. Restoring the gene's function corrected the working memory deficit and counteracting its deficiency also repaired neuronal circuit deficits in adult mice — suggesting clues for potential treatment strategies.

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E-cigarette flavors decrease perception of harm among youth

As more and more youth use electronic cigarettes, combined with research showing the health consequences of vaping — including nicotine addiction — researchers found that non-menthol flavors attract youth and adults to use e-cigarettes and that the use of flavored e-cigarettes contributes to multiple pathways linked to higher e-cigarette use among youth.

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The long arm of childhood conditions

Available research on the impact of a person's socioeconomic status during childhood suggests that the circumstances one grows up in matter a great deal for adult health. The results of a new study supports the notion of a 'long arm of childhood conditions' that remains invisible beyond mid-life but can affect health satisfaction later in life.

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