Drug delivery: Thermo-responsive protein hydrogel

Bio-engineering researchers have created a biocompatible, protein-based hydrogel that could serve as a drug delivery system durable enough to survive in the body for more than two weeks while providing sustained medication release. The research advances an area of biochemistry that is also critical to tissue engineering and regenerative medicine. Protein hydrogels are more biocompatible than synthetic ones and do not require potentially toxic chemical crosslinkers.

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New piece of Alzheimer's puzzle found

Scientists found two short peptides, or strings of amino acids, that when injected into mice with Alzheimer's disease daily for five weeks, significantly improved the mice's memory. The treatment also reduced some of the harmful physical changes in the brain that are associated with the disease.

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A safer way for police to test drug evidence

Scientists have demonstrated a way for police to quickly and safely test whether a baggie or other package contains illegal drugs without having to handle any suspicious contents directly. The new technique can limit the risk of accidental exposure to fentanyl and other highly potent drugs that can be dangerous if a small amount is accidentally inhaled.

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Sweet success of parasite survival could also be its downfall

Scientists have discovered how a parasite responsible for spreading a serious tropical disease protects itself from starvation once inside its human host. The findings provide a new understanding of the metabolism of the Leishmania parasite and this new knowledge could potentially be used in its eradication.

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Anesthetic drug sevoflurane improves sepsis outcomes, animal study reveals

Patients with sepsis often require surgery or imaging procedures under general anesthesia, yet there is no standard regimen for anesthetizing septic patients. Of volatile (inhaled) anesthetics, sevoflurane and isoflurane are the most commonly used drugs, despite their undetermined mechanisms of action. A novel study suggests that the type of drug used in general anesthesia could be critical to the survival of patients with sepsis.

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