Microbes and More
Ancient genomes provide insight into the genetic history of the second plague pandemic
Researchers have analyzed remains from ten archaeological sites in England, France, Germany, Russia, and Switzerland to gain insight into the different stages of the second plague pandemic and the genetic diversity of Yersinia pestis during and after the Black Death. The researchers reconstructed 34 Y. pestis genomes, tracing the genetic history of the bacterium, which revealed key insights into the initiation and progression of the second plague pandemic in Europe.
Read moreWhy multipartite viruses infect plants rather than animals
Being in between living and non-living, viruses are, in general, strange. Among viruses, multipartite viruses are among the most peculiar — their genome is not packed into one, but many, particles. Multipartite viruses primarily infect plants rather than animals. A recent article uses mathematical and computational models to explain this observation.
Read moreProtozoans and pathogens make for an infectious mix
The new observation that strains of V. cholerae can be expelled into the environment after being ingested by protozoa, and that these bacteria are then primed for colonization and infection in humans, could help explain why cholera is so persistent in aquatic environments. The disease-causing bacteria are protected in the protozoan gut and ejected into the environment in membrane-bound expelled food vacuoles (EFVs).
Read moreGlowing bacteria in anglerfish 'lamp' come from the water
New research shows that female deep-sea anglerfish's bioluminescent bacteria — which illuminate their 'headlamp' — most likely come from the water.
Read moreDid long ago tsunamis lead to mysterious, tropical fungal outbreak in Pacific northwest?
The Great Alaskan Earthquake of 1964 and the tsunamis it spawned may have washed a tropical fungus ashore, leading to a subsequent outbreak of often-fatal infections among people in coastal regions of the Pacific Northwest, according to a new article.
Read moreBabies have fewer respiratory infections if they have well-connected bacterial networks
Microscopic bacteria, which are present in all humans, cluster together and form communities in different parts of the body, such as the gut, lungs, nose and mouth. Now, for the first time, researchers have shown the extent to which these microbial communities are linked to each other across the body, and how these networks are associated with susceptibility to respiratory infections in babies.
Read moreThe flagellar hook: Making sense of bacterial motility
Researchers show how bacteria transmit motion from an inner motor to an outer tail through a flexible joint in the flagellum known as the hook. This finding could help in the fight against deadly bacterial infections. By better understanding how bacteria move, researchers may be able to improve disease prevention strategies.
Read moreORNL scientists shed light on microbial 'dark matter' with new approach
Scientists have demonstrated a way to isolate and grow targeted bacteria using genomic data, making strides toward resolving the grand challenge of uncultivated microbial 'dark matter' in which the vast majority of microorganisms remain unstudied in the laboratory.
Read morePotent antibody curbs Nipah and Hendra virus attack
A monoclonal antibody has been shown to impede the fusion machinery henipaviruses use to merge with the membrane of cells they are attempting to breach. The antibody halts the attack by blocking membrane fusion and the injection of the viral genome into the host cell. Researchers hope this discovery will pave the way toward preventing or treating Nipah or Hendra virus infections, which now have no vaccines or therapies for people. The main carriers are large bats called flying foxes.
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