Cambridge scientists have created a breakthrough material that can sense tiny chemical changes in the body, such as the increased acidity during an arthritis flare-up, and release drugs exactly when and where they’re needed. By mimicking cartilage while delivering medication, this smart gel could ease pain, reduce side effects, and provide continuous treatment for millions of arthritis sufferers.
Read moreFor decades, scientists believed Alzheimer’s was driven mainly by sticky protein plaques and tangles in the brain. Now Purdue researchers have revealed a hidden culprit: fat. They found that brain immune cells can become clogged with fat, leaving them too weak to fight off disease. By clearing out this fat and restoring the cells’ defenses, researchers may have uncovered an entirely new way to combat Alzheimer’s — shifting the focus from plaques alone to how the brain handles fat.
Read moreResearchers found that magic mushrooms and fiber caps independently evolved different biochemical pathways to create psilocybin. This convergence shows nature’s ingenuity, but the reason why remains unknown—possibly predator deterrence. Beyond evolutionary mystery, the discovery provides new enzyme tools for biotech, with promising applications for producing psilocybin-based medicines.
Read moreScientists have discovered that cancer uses a hidden hormone to switch off the body’s natural defenses, allowing tumors to grow unchecked. By uncovering this secret signal, they found a way to block it and restore the immune system’s ability to fight back. The breakthrough not only hints at powerful new cancer treatments but also suggests the same pathway could someday be used to calm autoimmune diseases.
Read moreNew research shows that cancer cells don’t just grow; they adapt when stressed. When squeezed inside tissues, they transform into more invasive, drug-resistant versions of themselves. A protein called HMGB2 helps flip this dangerous switch, giving the cells new powers to escape. The findings reveal how the tumor’s environment itself can drive cancer’s deadly flexibility.
Read moreUniversity of Maine researchers developed a new process to make HBL, a key ingredient in many medicines, from renewable glucose instead of petroleum. The approach not only lowers drug production costs but also reduces emissions.
Read moreA sweeping analysis of nearly 10,000 patients reveals that knee braces, hydrotherapy, and exercise stand out as the most effective non-drug therapies for knee osteoarthritis. Unlike common pain medications that carry risks, these low-cost and accessible options reduce pain, improve mobility, and could shift treatment guidelines toward safer, drug-free approaches.
Read moreResearchers have created a two-stage acne patch with tiny arrowhead-shaped spikes that deliver healing compounds directly under the skin. Trials showed pimples vanished in seven days, and the technology may expand to treat other conditions.
Read moreDiabetes affects millions of Americans, and many don’t even realize they have it. Instead of relying on costly and time-consuming lab tests, scientists at Penn State have developed a breath sensor that can detect diabetes and prediabetes within minutes by measuring acetone levels. Built from laser-induced graphene and zinc oxide, the sensor is lightweight, inexpensive, and designed to overcome challenges like humidity in exhaled breath.
Read moreNew research reveals lymphoma can directly accelerate aging in the immune system and vital organs, independent of treatments like chemotherapy. The changes, sometimes reversible, highlight a hidden dimension of cancer—and possible new paths for intervention.
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